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NIPS Test | Non-Invasive Prenatal Screening | Henotic Diagnostics
NIPS Test: Fast & Precise Non-Invasive Prenatal Screening
Advanced Cell-Free Fetal DNA NIPS Test Screening Experts
First of all, the NIPS Test (Non-Invasive Prenatal Screening) is an advanced cell-free fetal DNA test performed as early as week 10 of pregnancy. Essentially, Next-Generation Sequencing (NGS) of maternal blood isolates placental DNA to evaluate fetal chromosomal health with over 99% accuracy. As a result, expectant parents screen for Down syndrome, Edwards syndrome, and Patau syndrome without any risk of miscarriage.
Book your NIPS Test at Henotic Diagnostics for reliable prenatal peace of mind. Furthermore, our accredited diagnostic facility operates 24/7 with dedicated home sample collection services.
Cell-Free Fetal DNA (cfDNA) Next-Generation Sequencing
🩸 Sample Type
10 ml Maternal Blood in cfDNA Preservation Tube
💰 Price Range
₹14,500 – ₹24,500 (All-inclusive diagnostic fee)
📄 Report TAT
5 to 7 Days (Includes geneticist interpretation)
🕐 Gestational Age
From 10 Weeks Onward (Singles & Twins)
👩⚕️ Specialist
Dr. Pratibha Patil — Fetal Medicine Specialist
🍽️ Fasting
No Fasting Required (Normal diet allowed)
💳 Insurance
Reimbursement Documentation Support provided
🏅 Accreditation
NABL Accredited · ISO Certified · PCPNDT Compliant
NIPS Test Quality Standards & Certifications
First, 5.0 Google Rated
Second, >99% Down Syndrome Accuracy
In addition, Zero Miscarriage Risk
Furthermore, NABL Accredited
Also, Screened from 10 Weeks
Moreover, Microdeletion Panel Included
Finally, ISO Certified
Overview of NIPS Test (Non-Invasive Prenatal Screening)
To begin with, the NIPS Test represents the safest and most accurate non-invasive screening method for fetal chromosomal conditions. At the same time, experts at Henotic Diagnostics analyze cell-free fetal DNA (cfDNA) circulating in maternal plasma to deliver clinical clarity.
What Does NIPS Test Evaluate?
Specifically, NIPS evaluates fetal chromosomal counts for Trisomy 21 (Down syndrome), Trisomy 18 (Edwards syndrome), Trisomy 13 (Patau syndrome), sex chromosome aneuploidies (Turner 45,X, Klinefelter 47,XXY), and microdeletions. Consequently, obstetricians provide high-precision screening without risking invasive procedures. Furthermore, high-depth NGS achieves >99.9% negative predictive value. As a result, expectant mothers enjoy complete peace of mind. In fact, to review clinical guidelines, consult the ACOG Prenatal Screening resource.
Furthermore, comfortable reception lounge ensuring a calm, stress-free sample collection for pregnant mothers
What is an NIPS Test?
In general, NIPS is a revolutionary screening technology that analyzes fragments of placental DNA present in maternal blood. Essentially, placental cell-free fetal DNA enters maternal circulation by week 7 and reaches sufficient concentration (>4% fetal fraction) by week 10. Specifically, Next-Generation Sequencers count relative chromosome ratios in blood plasma. Therefore, bioinformatic algorithms determine whether fetal trisomy risk is low or elevated. Additionally, NIPS avoids invasive needle insertion into the amniotic sac.
Additionally, high-throughput NGS platform measures cell-free fetal DNA ratios with extreme sensitivity
What Does an NIPS Test Check?
Overall, NIPS screening evaluates core autosomal trisomies, sex chromosome conditions, and structural microdeletions:
Key Chromosomal Conditions Screened
✓
Trisomy 21 (Down Syndrome): First, detects extra chromosome 21 with >99% detection sensitivity.
✓
Trisomy 18 (Edwards) & Trisomy 13 (Patau): Second, screens for severe developmental trisomies with high specificity.
✓
Sex Chromosome Aneuploidies: In addition, identifies Monosomy X (Turner syndrome), XXY (Klinefelter), and XXX/XYY conditions.
✓
Microdeletion Syndromes: Finally, screens for 22q11.2 deletion (DiGeorge), 1p36 deletion, and Cri-du-chat syndromes.
In addition, advanced bioinformatic software calculates precise risk scores for Trisomies 21, 18, and 13
When Is NIPS Test Recommended?
For example, obstetricians and maternal-fetal specialists recommend NIPS screening for all expectant mothers starting at 10 weeks gestation. In particular, NIPS is strongly advised for mothers aged 35 or older at delivery. Moreover, it is recommended if double marker serum screening or NT ultrasound indicates intermediate or high risk. In addition, mothers with a prior pregnancy affected by trisomy select NIPS for early reassurance.
Clinical Distinction: NIPS Screening vs. Invasive Amniocentesis
Why NIPS Replaces Invasive Screening for Most Pregnancies
Ideally, mothers should start with non-invasive NIPS if they wish to avoid the 1 in 200 procedure-related miscarriage risk of amniocentesis. In addition, if NIPS returns low risk, invasive procedures are completely avoided. Indeed, non-invasive testing offers maximum safety for your baby.
NIPS Test Cost Guide
Prenatal Diagnostic Service
Approximate Cost (₹)
NIPS Test Basic (Trisomies 21, 18, 13)
First, basic NIPS test pricing is ₹14,500 – ₹18,500.
In addition, twin pregnancy NIPS costs ₹18,500 – ₹22,500.
Pre & Post-Test Genetic Counseling
Finally, expert genetic consultation fee is ₹1,000 – ₹1,500.
Comparison: NIPS Test vs. First Trimester Combined Screening
On one hand, First Trimester Combined Double Marker screening achieves only 85-90% detection with a 5% false positive rate, whereas NIPS achieves >99% detection with less than 0.1% false positives. Consequently, NIPS significantly reduces unnecessary invasive procedures.
Feature
NIPS Test (cfDNA NGS)
Combined Serum Marker Screening
Down Syndrome Sensitivity
First, NIPS achieves >99% detection sensitivity.
However, Double Marker detects only 85% – 90%.
False Positive Rate
Second, NIPS false positive rate is extremely low (<0.1%).
In contrast, serum screening has a 5% false positive rate.
Earliest Testing Window
In addition, NIPS is performed from 10 weeks gestation.
Meanwhile, serum screening is performed at 11-13 weeks.
Fetal Miscarriage Risk
Finally, zero procedure-related risk to pregnancy.
Likewise, zero procedure-related risk (blood draw).
Frequently Asked Questions
Is an NIPS Test safe for my baby?▼
However, routine maternal blood draw carries zero risk of miscarriage for the fetus.
Do I need to fast before an NIPS Test?▼
Because cell-free fetal DNA sequencing is independent of blood glucose, fasting is unnecessary.
How early in pregnancy can I get an NIPS Test?▼
Generally, NIPS screening is performed accurately from 10 weeks of pregnancy onward.
How long until I receive diagnostic results?▼
Fortunately, detailed clinical NIPS reports are delivered within 5 to 7 business days.
What is the cost of an NIPS Test?▼
Overall, a high-precision NIPS Test ranges from ₹14,500 to ₹24,500 all-inclusive.
Quick Appointment Booking
Schedule your NIPS Test with accredited prenatal genomic experts.
MBBS, MD (Fetal Medicine) · 15+ Years Clinical Experience
Furthermore, your NIPS Test cell-free fetal DNA data is evaluated by senior fetal medicine specialists and geneticists following PCPNDT guidelines. Consequently, detailed reports provide obstetricians with trustworthy clinical guidance.
Real feedback from expectant parents who completed NIPS screening with us.
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“At 35 years old, getting an NIPS Test gave us complete anxiety relief. Furthermore, Dr. Pratibha Patil’s team provided our report within 5 days with zero hassle.”
– Anita V.
Verified Patient Review
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“The home phlebotomy sample collection was extremely smooth and comfortable. In addition, the genetic counselor answered every question.”
– Sneha P.
Verified Patient Review
⭐⭐⭐⭐⭐
“Transparent price and PCPNDT compliant facility. Our gynecologist specifically recommended Henotic Diagnostics for NIPS.”
You can book your NIPS Test appointment at our Navi Mumbai center through multiple convenient channels: call us directly at 088793 27184, send a WhatsApp message for instant booking, or use the online booking form on our website. Walk-in appointments are also welcome based on slot availability. We recommend advance booking to ensure zero wait times.
Yes, Henotic Diagnostics Navi Mumbai is empanelled with all major insurance companies and TPAs (Third Party Administrators) including Star Health, ICICI Lombard, New India Assurance, HDFC Ergo, Max Bupa, Bajaj Allianz, and many more. We offer cashless processing for NIPS Test where applicable. Please carry your insurance card and a valid ID for seamless processing.
At Henotic Diagnostics Navi Mumbai, most NIPS Test reports are delivered within 2-6 hours for routine tests. Critical and urgent reports are expedited on a priority basis. All reports are delivered digitally via WhatsApp, email, and our secure online patient portal. Hard copies are also available at the center upon request. You will receive an SMS/WhatsApp notification the moment your report is ready.
Henotic Diagnostics Navi Mumbai operates 24 hours a day, 7 days a week, including Sundays and public holidays. This means you can schedule your NIPS Test at a time that is most convenient for you — early morning, late evening, or even overnight for emergency requirements. Our radiology and pathology departments maintain round-the-clock availability.
Yes, Henotic Diagnostics Navi Mumbai is fully accredited by NABL (National Accreditation Board for Testing and Calibration Laboratories) and ISO 9001:2015 certified. Our radiology equipment also complies with AERB (Atomic Energy Regulatory Board) safety standards. These accreditations ensure that every NIPS Test performed at our facility meets the highest national and international quality benchmarks for accuracy, safety, and reliability.
